These scientific figures accompany a review article “Immunity against Fungi” in the JCI insight, published June 6, 2017. These are created to help explain the mechanism of antifungal immune response as well as depicting anatomic sites that are commonly affected by the fungal genera. Read full article Read full article here.
The team sat down with the client to understand the background and the mechanism in which the client is hoping to depict in the figure. Here, we display the client sketches and instructions given during our initial consultation.
After an attempt to start with the sketch, we quickly realized that we first need deeper understanding of the numerous proteins that are to be drawn in the figure. By using the Protein Data Bank (PDB), we scraped data to understand the characteristics of each protein as well as how they appear different in their 3D structure.
Using the information collected during the research phase, we reconstructed a unique pseudo-3D look of each protein. Here, we list the 2D assets built to be used in the final figure. The color red is provided to clarify the nucks and cranies however the color of each protein hasn't been decided at this point.
Combining pencil sketch and digital technique, a sketch is created to be reviewed by the client. We primarily focused on organizing the information in a more intuitive flow. First, by positioning the macrophage on the left and Th17 cell on the right, we are able to create a left-to-right flow similar to how we read text in western culture. We created a callout in the middle and have some protein spill out to enhancing the flow of the story. Similar to this, we rearranged the information in the 2nd figure to create a cohesive yet engaging look of the story.